Effects of computer-assisted navigation versus conventional total knee arthroplasty on the levels of inflammation markers: A prospective study.

ABSTRACT: Total knee arthroplasty (TKA) is a well-established modality for the treatment of advanced knee osteoarthritis (OA). However, the detrimental effects of intramedullary reaming used in conventional TKA for distal femur cutting are of concern. Avoiding intramedullary reaming with the use of computer-assisted navigation TKA can not only provide superior prosthetic alignment, but also mitigate perioperative blood loss and the dissipation of marrow emboli. We quantified local and systemic concentrations of inflammation markers for both techniques. Forty-four participants undergoing computer-assisted navigation and 53 receiving conventional TKA for advanced knee OA were recruited between 2013/02/08 and 2015/12/09. Blood samples were collected from all participants at baseline then again at 24 an

SUBMITTER: Kuo SJ 

PROVIDER: S-EPMC5951551 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature