Measuring human placental blood flow with multidelay 3D GRASE pseudocontinuous arterial spin labeling at 3T.

ABSTRACT: BACKGROUND:Placenta influences the health of both a woman and her fetus during pregnancy. Maternal blood supply to placenta can be measured noninvasively using arterial spin labeling (ASL). PURPOSE:To present a multidelay pseudocontinuous arterial spin labeling (pCASL) combined with a fast 3D inner-volume gradient- and spin-echo (GRASE) imaging technique to simultaneously measure placental blood flow (PBF) and arterial transit time (ATT), and to study PBF and ATT evolution with gestational age during the second trimester. The PBF values were compared with uterine arterial Doppler ultrasound to assess its potential clinical utility. STUDY TYPE:This was a prospective study. SUBJECTS:Thirty-four pregnant women. FIELD STRENGTH/SEQUENCE:Multidelay 3D inner-volume GRASE pCASL sequence on 3T MR s

SUBMITTER: Shao X 

PROVIDER: S-EPMC5951737 | biostudies-literature | 2018 Jun

REPOSITORIES: biostudies-literature