N-3 Fatty Acid Supplementation for the Treatment of Dry Eye Disease.

ABSTRACT:

Background

Dry eye disease is a common chronic condition that is characterized by ocular discomfort and visual disturbances that decrease quality of life. Many clinicians recommend the use of supplements of n-3 fatty acids (often called omega-3 fatty acids) to relieve symptoms.

Methods

In a multicenter, double-blind clinical trial, we randomly assigned patients with moderate-to-severe dry eye disease to receive a daily oral dose of 3000 mg of fish-derived n-3 eicosapentaenoic and docosahexaenoic acids (active supplement group) or an olive oil placebo (placebo group). The primary outcome was the mean change from baseline in the score on the Ocular Surface Disease Index (OSDI; scores range from 0 to 100, with higher scores indicating greater symptom severity), which was based

SUBMITTER: Dry Eye Assessment and Management Study Research Group 

PROVIDER: S-EPMC5952353 | biostudies-literature | 2018 May

REPOSITORIES: biostudies-literature