Low-cost HPV testing and the prevalence of cervical infection in asymptomatic populations in Guatemala.

ABSTRACT:

Background

A low cost and accurate method for detecting high-risk (HR) human papillomavirus (HPV) is important to permit HPV testing for cervical cancer prevention. We used a commercially available HPV method (H13, Hybribio) which was documented to function accurately in a reduced volume of cervical specimen to determine the most prevalent HPV types and the distribution of HPV infections in over 1795 cancer-free women in Guatemala undergoing primary screening for cervical cancer by cytology.

Methods

HR-HPV detection was attempted in cervical samples from 1795 cancer-free women receiving Pap smears using the Hybribio™ real-time PCR assay of 13 HR types. The test includes a globin gene internal control. HPV positive samples were sequenced to determine viral type. Age-specific

SUBMITTER: Lou H 

PROVIDER: S-EPMC5952444 | biostudies-literature | 2018 May

REPOSITORIES: biostudies-literature