Gene regulation associated with sexual development and female fertility in different isolates of <i>Trichoderma reesei</i>.

ABSTRACT:

Background

Trichoderma reesei is one of the most frequently used filamentous fungi in industry for production of homologous and heterologous proteins. The ability to use sexual crossing in this fungus was discovered several years ago and opens up new perspectives for industrial strain improvement and investigation of gene regulation.

Results

Here we investigated the female sterile strain QM6a in comparison to the fertile isolate CBS999.97 and backcrossed derivatives of QM6a, which have regained fertility (FF1 and FF2 strains) in both mating types under conditions of sexual development. We found considerable differences in gene regulation between strains with the CBS999.97 genetic background and the QM6a background. Regulation patterns of QM6a largely clustered with th

SUBMITTER: Dattenbock C 

PROVIDER: S-EPMC5952832 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature