MiRDis: a Web tool for endogenous and exogenous microRNA discovery based on deep-sequencing data analysis.

ABSTRACT: Small RNA sequencing is the most widely used tool for microRNA (miRNA) discovery, and shows great potential for the efficient study of miRNA cross-species transport, i.e., by detecting the presence of exogenous miRNA sequences in the host species. Because of the increased appreciation of dietary miRNAs and their far-reaching implication in human health, research interests are currently growing with regard to exogenous miRNAs bioavailability, mechanisms of cross-species transport and miRNA function in cellular biological processes. In this article, we present microRNA Discovery (miRDis), a new small RNA sequencing data analysis pipeline for both endogenous and exogenous miRNA detection. Specifically, we developed and deployed a Web service that supports the annotation and expression profili

SUBMITTER: Zhang H 

PROVIDER: S-EPMC5952930 | biostudies-literature | 2018 May

REPOSITORIES: biostudies-literature