Self-reported neglect, amygdala volume, and symptoms of anxiety in adolescent boys.

ABSTRACT: Experiences of psychosocial neglect affect the developing brain and may place individuals at increased risk for anxiety. The majority of research in this area has focused on children who have experienced severe psychosocial deprivation; it is not clear whether typical variation in neglect experienced in community samples would have the same neurobiological consequences as those documented in extreme samples. The present study examined the associations among self-reported childhood neglect, amygdala volume, and anxiety symptoms in a community sample of 138 adolescents ages 9-15 years (43% male). Linear mixed modeling yielded a three-way interaction of neglect, sex, and brain hemisphere, reflecting a significant positive association between neglect and right amygdala volume in boys. Addition

SUBMITTER: Roth MC 

PROVIDER: S-EPMC5953811 | biostudies-literature | 2018 Jun

REPOSITORIES: biostudies-literature