Characterization of In Vivo Retinal Lesions of Diabetic Retinopathy Using Adaptive Optics Scanning Laser Ophthalmoscopy.

ABSTRACT:

Purpose

To characterize hallmark diabetic retinopathy (DR) lesions utilizing adaptive optics scanning laser ophthalmoscopy (AOSLO) and to compare AOSLO findings with those on standard imaging techniques.

Methods

Cross-sectional study including 35 eyes of 34 study participants. AOSLO confocal and multiply scattered light (MSL) imaging were performed in eyes with DR. Color fundus photographs (CF), infrared images of the macula (Spectralis, Heidelberg), and Spectralis spectral domain optical coherence tomography SDOCT B-scans of each lesion were obtained and registered to corresponding AOSLO images.

Main outcome measures

Individual lesion characterization by AOSLO imaging. AOSLO appearance was compared with CF and SDOCT imaging.

Results

Characterized lesions encom

SUBMITTER: Karst SG 

PROVIDER: S-EPMC5954931 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature