Sonographic visualization of nipple blood flow can help differentiate Paget disease from benign eczematous nipple lesions.

ABSTRACT:

Purpose

Paget disease of the breast is a rare cancer that originates from the nipple-areolar complex. It is often overlooked and misdiagnosed as benign chronic eczema of the nipple. We aimed to retrospectively verify whether blood flow analysis using Doppler sonography was useful for detecting the presence of Paget disease.

Methods

In this retrospective study, 12 patients with pathologically proven unilateral nipple eczematous lesions (seven with Paget disease and five with simple dermatitis) were included. Nipple blood flow signal was observed using Doppler sonography, and the detected blood flow signals were quantified using digitally recorded images. Quantified blood flow ratio and pathologically examined capillary density were evaluated between affected and unaffected ni

SUBMITTER: Ogata H 

PROVIDER: S-EPMC5955580 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature