Chemical fingerprints of cold physical plasmas - an experimental and computational study using cysteine as tracer compound.

ABSTRACT: Reactive oxygen and nitrogen species released by cold physical plasma are being proposed as effectors in various clinical conditions connected to inflammatory processes. As these plasmas can be tailored in a wide range, models to compare and control their biochemical footprint are desired to infer on the molecular mechanisms underlying the observed effects and to enable the discrimination between different plasma sources. Here, an improved model to trace short-lived reactive species is presented. Using FTIR, high-resolution mass spectrometry, and molecular dynamics computational simulation, covalent modifications of cysteine treated with different plasmas were deciphered and the respective product pattern used to generate a fingerprint of each plasma source. Such, our experimental model al

SUBMITTER: Lackmann JW 

PROVIDER: S-EPMC5955931 | biostudies-literature | 2018 May

REPOSITORIES: biostudies-literature