Short-term temporal memory in idiopathic and Parkin-associated Parkinson's disease.

ABSTRACT: In a rapidly changing environment, we often know when to do something before we have to do it. This preparation in the temporal domain is based on a 'perception' of elapsed time and short-term memory of previous stimulation in a similar context. These functions could be perturbed in Parkinson's disease. Therefore, we investigated their role in eye movement preparation in sporadic Parkinson's disease and in a very infrequent variant affecting the Parkin gene. We used a simple oculomotor task where subjects had to orient to a visual target and movement latency was measured. We found that in spite of an increased average reaction time, the influence of elapsed time on movement preparation was similar in controls and the two groups of PD patients. However, short-term temporal memory of previou

SUBMITTER: Degos B 

PROVIDER: S-EPMC5956077 | biostudies-literature | 2018 May

REPOSITORIES: biostudies-literature