Automated structure and flow measurement - a promising tool in nailfold capillaroscopy.

ABSTRACT:

Objectives

Despite increasing interest in nailfold capillaroscopy, objective measures of capillary structure and blood flow have been little studied. We aimed to test the hypothesis that structural measurements, capillary flow, and a combined measure have the predictive power to separate patients with systemic sclerosis (SSc) from those with primary Raynaud's phenomenon (PRP) and healthy controls (HC).

Methods

50 patients with SSc, 12 with PRP, and 50 HC were imaged using a novel capillaroscopy system that generates high-quality nailfold images and provides fully-automated measurements of capillary structure and blood flow (capillary density, mean width, maximum width, shape score, derangement and mean flow velocity). Population statistics summarise the differences between t

SUBMITTER: Berks M 

PROVIDER: S-EPMC5956308 | biostudies-literature | 2018 Jul

REPOSITORIES: biostudies-literature