Patient reported dry mouth: Instrument comparison and model performance for correlation with quality of life in head and neck cancer survivors.

ABSTRACT: PURPOSE:To identify a clinically meaningful cut-point for the single item dry mouth question of the MD Anderson Symptom Inventory-Head and Neck module (MDASI-HN). METHODS:Head and neck cancer survivors who had received radiation therapy (RT) completed the MDASI-HN, the University of Michigan Hospital Xerostomia Questionnaire (XQ), and the health visual analog scale (VAS) of the EuroQol Five Dimension Questionnaire (EQ-5D). The Bayesian information criteria (BIC) were used to test the prediction power of each tool for EQ-5D VAS. The modified Breiman recursive partitioning analysis (RPA) was used to identify a cut point of the MDASI-HN dry mouth score (MDASI-HN-DM) with EQ-5D VAS, using a ROC-based approach; regression analysis was used to confirm the threshold effect size. RESULTS:Two-hundr

SUBMITTER: MD Anderson Head and Neck Cancer Symptom Working Group 

PROVIDER: S-EPMC5957088 | biostudies-literature | 2018 Jan

REPOSITORIES: biostudies-literature