In vitro comparison of three common essential oils mosquito repellents as inhibitors of the Ross River virus.

ABSTRACT:

Background

The essential oils of Cymbopogon citratus (CC), Pelargonium graveolens (PG) and Vetiveria zizanioides (VZ) are commonly used topically to prevent mosquito bites and thus the risk of infection by their vectored pathogens such as arboviruses. However, since mosquito bites are not fully prevented, the effect of these products on the level of viral infection remains unknown.

Objectives

To evaluate in vitro the essentials oils from Reunion Island against one archetypal arbovirus, the Ross River virus (RRV), and investigate the viral cycle step that was impaired by these oils.

Methods

The essential oils were extracted by hydrodistillation and analyzed by a combination of GC-FID and GC×GC-TOF MS techniques. In vitro studies were performed on HEK293T cells to deter

SUBMITTER: Ralambondrainy M 

PROVIDER: S-EPMC5957362 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature