Altered N170 and mood symptoms in bipolar disorder: An electrophysiological study of configural face processing.

ABSTRACT: Altered social behavior during mood episodes in bipolar disorder often has detrimental and long-lasting interpersonal consequences. Abnormal face processing may play a role in linking brain functions to clinical symptoms and behavior. This study aimed to understand configural face processing in bipolar disorder as a function of basic communicative attributes of the face and mood symptoms using event-related brain potentials (ERPs). Forty-two participants with bipolar I disorder (BP) and 43 healthy controls (HC) viewed face stimuli varying in emotion (neutral or fearful), head orientation (forward or deviated), and gaze direction (direct or averted) while ERPs were recorded. Configural face processing was indexed by the N170 wave. BP participants had comparable overall N170 amplitude and pe

SUBMITTER: Tso IF 

PROVIDER: S-EPMC5957763 | biostudies-literature | 2017 Nov

REPOSITORIES: biostudies-literature