Association between urinary sodium excretion and uric acid, and its interaction on the risk of prehypertension among Chinese young adults.

ABSTRACT: High uric acid (UA) level and high salt intake are reportedly associated with cardiovascular disease. This study investigated the association between UA and urinary sodium excretion, as well as its interaction on the risk of prehypertension. A total of 1869 participants without hypertension were recruited from a previously established cohort in Shaanxi Province, China. The participants were classified as normotensive or prehypertensive on the basis of their blood pressure. Increasing quartiles of sodium excretion were associated with high urinary UA/creatinine levels in prehypertensive participants. Estimated sodium excretion positively correlated with urinary UA/creatinine excretions in the prehypertensive group. In addition, the multivariate-adjusted odds ratios for prehypertension compa

SUBMITTER: Wang Y 

PROVIDER: S-EPMC5958063 | biostudies-literature | 2018 May

REPOSITORIES: biostudies-literature