Sensory representation of an auditory cued tactile stimulus in the posterior parietal cortex of the mouse.

ABSTRACT: Sensory association cortices receive diverse inputs with their role in representing and integrating multi-sensory content remaining unclear. Here we examined the neuronal correlates of an auditory-tactile stimulus sequence in the posterior parietal cortex (PPC) using 2-photon calcium imaging in awake mice. We find that neuronal subpopulations in layer 2/3 of PPC reliably represent texture-touch events, in addition to auditory cues that presage the incoming tactile stimulus. Notably, altering the flow of sensory events through omission of the cued texture touch elicited large responses in a subset of neurons hardly responsive to or even inhibited by the tactile stimuli. Hence, PPC neurons were able to discriminate not only tactile stimulus features (i.e., texture graininess) but also betwee

SUBMITTER: Mohan H 

PROVIDER: S-EPMC5958066 | biostudies-literature | 2018 May

REPOSITORIES: biostudies-literature