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A Fatal Case of Candida auris and Candida tropicalis Candidemia in Neutropenic Patient.


ABSTRACT: We report a fatal case of Candida auris that was involved in mixed candidemia with Candida tropicalis, isolated from the blood of a neutropenic patient. Identification of both isolates was confirmed by amplification and sequencing of internal transcribed spacer and D1/D2 domain of large subunit in rRNA gene. Antifungal susceptibility test by E-test method revealed that C. auris was resistant to amphotericin B, anidulafungin, caspofungin, fluconazole, itraconazole and voriconazole. On the other hand, C. tropicalis was sensitive to all antifungal tested. The use of chromogenic agar as isolation media is vital in detecting mixed candidemia.

SUBMITTER: Mohd Tap R 

PROVIDER: S-EPMC5958168 | biostudies-literature | 2018 Jun

REPOSITORIES: biostudies-literature

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A Fatal Case of Candida auris and Candida tropicalis Candidemia in Neutropenic Patient.

Mohd Tap Ratna R   Lim Teck Choon TC   Kamarudin Nur Amalina NA   Ginsapu Stephanie Jane SJ   Abd Razak Mohd Fuat MF   Ahmad Norazah N   Amran Fairuz F  

Mycopathologia 20180130 3


We report a fatal case of Candida auris that was involved in mixed candidemia with Candida tropicalis, isolated from the blood of a neutropenic patient. Identification of both isolates was confirmed by amplification and sequencing of internal transcribed spacer and D1/D2 domain of large subunit in rRNA gene. Antifungal susceptibility test by E-test method revealed that C. auris was resistant to amphotericin B, anidulafungin, caspofungin, fluconazole, itraconazole and voriconazole. On the other h  ...[more]

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