Objectively measured physical activity and cardiac biomarkers: A cross sectional population based study in older men.

ABSTRACT:

Background

N-terminal pro-brain natriuretic peptide (NT-proBNP) and high sensitivity Troponin T (hsTnT) are markers of cardiac injury used in diagnosis of heart failure and myocardial infarction respectively, and associated with increased risk of cardiovascular disease. Since physical activity is protective against cardiovascular disease and heart failure, we investigated whether higher levels of physical activity, and less sedentary behaviour were associated with lower NT-proBNP and hsTnT.

Methods and results

Cross sectional study of 1130 men, age 70-91years, from the British Regional Heart Study, measured in 2010-2012. Fasting blood samples were analysed for NT-proBNP and hsTnT. Physical activity and sedentary behaviour were measured using ActiGraph GT3X accelerometers. Re

SUBMITTER: Parsons TJ 

PROVIDER: S-EPMC5958950 | biostudies-literature | 2018 Mar

REPOSITORIES: biostudies-literature