A new route to synthesize aryl acetates from carbonylation of aryl methyl ethers.

ABSTRACT: Ether bond activation is very interesting because the synthesis of many valuable compounds involves conversion of ethers. Moreover, C-O bond cleavage is also very important for the transformation of biomass, especially lignin, which abundantly contains ether bonds. Developing efficient methods to activate aromatic ether bonds has attracted much attention. However, this is a challenge because of the inertness of aryl ether bonds. We proposed a new route to activate aryl methyl ether bonds and synthesize aryl acetates by carbonylation of aryl methyl ethers. The reaction could proceed over RhCl₃ in the presence of LiI and LiBF₄, and moderate to high yields of aryl acetates could be obtained from transformation of various aryl methyl ethers with different substituents. It

SUBMITTER: Mei Q 

PROVIDER: S-EPMC5959316 | biostudies-literature | 2018 May

REPOSITORIES: biostudies-literature