Genome-wide detection of selection signatures in Chinese indigenous Laiwu pigs revealed candidate genes regulating fat deposition in muscle.

ABSTRACT:

Background

Currently, genome-wide scans for positive selection signatures in commercial breed have been investigated. However, few studies have focused on selection footprints of indigenous breeds. Laiwu pig is an invaluable Chinese indigenous pig breed with extremely high proportion of intramuscular fat (IMF), and an excellent model to detect footprint as the result of natural and artificial selection for fat deposition in muscle.

Result

In this study, based on GeneSeek Genomic profiler Porcine HD data, three complementary methods, F_ST, iHS (integrated haplotype homozygosity score) and CLR (composite likelihood ratio), were implemented to detect selection signatures in the whole genome of Laiwu pigs. Totally, 175 candidate selected regions were obtained by at lea

SUBMITTER: Chen M 

PROVIDER: S-EPMC5960162 | biostudies-literature | 2018 May

REPOSITORIES: biostudies-literature