High-Dose Chemotherapy with Stem Cell Rescue in Desmoplastic Small Round Cell Tumor: A Single-Institution Experience and Review of the Literature.

ABSTRACT:

Purpose

Desmoplastic small round cell tumor (DSRCT) is a rare cancer that predominantly affects males averaging 21 years of age at the time of diagnosis. We describe four cases from our institution and place them within the context of a comprehensive review of the literature.

Patients and methods

Study population included any patient who received treatment at Children's Hospital at Montefiore (CHAM) with histologic diagnosis of DSRCT. A search of the electronic databases PubMed, Cochrane Central Register of Controlled Trials, MEDLINE, and EMBASE for the terms "desmoplastic" AND "small" AND "round" AND "cell" AND "tumor" was performed.

Results

One CHAM patient died of disease at 39 months, one patient has relapsed disease at 40 months, and two patients have no evidence

SUBMITTER: Bailey K 

PROVIDER: S-EPMC5960572 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature