Lateral prefrontal cortex lesion impairs regulation of internally and externally directed attention.

ABSTRACT: Our capacity to flexibly shift between internally and externally directed attention is crucial for successful performance of activities in our daily lives. Neuroimaging studies have implicated the lateral prefrontal cortex (LPFC) in both internally directed processes, including autobiographical memory retrieval and future planning, and externally directed processes, including cognitive control and selective attention. However, the causal involvement of the LPFC in regulating internally directed attention states is unknown. The current study recorded scalp EEG from patients with LPFC lesions and healthy controls as they performed an attention task that instructed them to direct their attention either to the external environment or their internal milieu. We compared frontocentral midline the

SUBMITTER: Kam JWY 

PROVIDER: S-EPMC5960633 | biostudies-literature | 2018 Jul

REPOSITORIES: biostudies-literature