White matter hyperintensities and their subtypes in patients with carotid artery stenosis: a systematic review and meta-analysis.

ABSTRACT: OBJECTIVE:We aimed to perform a systematic review and meta-analysis to clarify the association between white matter hyperintensities (WMHs) and carotid artery (CA) stenosis. STUDY DESIGN:Systematic review and meta-analysis. PARTICIPANTS:CA stenosis was set at ≥50%, and WMHs were assessed by MRI and evaluated quantitatively or semiquantitatively. DATA SOURCES:A comprehensive literature search was performed in PubMed, EMBASE and Cochrane Library for studies evaluating the association between WMHs and CA stenosis ≥50% from inception to 13 September 2017. MAIN OUTCOMES AND MEASURES:Standardised mean difference (SMD) with 95% CI was used to evaluate the association between WMHs and CA stenosis. Results were presented in a forest plot with a fixed-effects model or random-effects model. We assess

SUBMITTER: Ye H 

PROVIDER: S-EPMC5961568 | biostudies-literature | 2018 May

REPOSITORIES: biostudies-literature