Diarrheagenic Escherichia coli and Acute Gastroenteritis in Children in Davidson County, Tennessee, United States: A Case-control Study.

ABSTRACT:

Background

Diarrheagenic Escherichia coli (DEC) is an important cause of acute gastroenteritis in children; however, there is limited information available on the epidemiology, phylogenetics, serotyping and antibiotic susceptibility of DEC in children in the United States. The aim of this study was to determine the molecular epidemiology of DEC among children with and without acute gastroenteritis in Davidson County, Tennessee.

Methods

This prospective, frequency matched, case-control study recruited subjects 15 days to 17 years of age and detected DEC with polymerase chain reaction from stool samples. Additional testing was done to define phylogenetics and antibiotics resistance.

Results

Among 1267 participants, 857 cases and 410 controls, 5.5% were positive for at l

SUBMITTER: Imdad A 

PROVIDER: S-EPMC5962020 | biostudies-literature | 2018 Jun

REPOSITORIES: biostudies-literature