Use of Nonantiretroviral Medications That May Impact Neurocognition: Patterns and Predictors in a Large, Long-Term HIV Cohort Study.

ABSTRACT:

Background

Neurocognitive impairment is a frequent and often disabling comorbidity of HIV infection. In addition to antiretroviral therapies, individuals with HIV infection may commonly use nonantiretroviral medications that are known to cause neurocognitive adverse effects (NC-AE). The contribution of NC-AE to neurocognitive impairment is rarely considered in the context of HIV and could explain part of the variability in neurocognitive performance among individuals with HIV.

Setting

Women's Interagency HIV Study, a prospective, multisite, observational study of US women with and without HIV.

Methods

After a literature review, 79 medications (excluding statins) with NC-AE were identified and reported by Women's Interagency HIV Study participants. We examined factors

SUBMITTER: Radtke KK 

PROVIDER: S-EPMC5962283 | biostudies-literature | 2018 Jun

REPOSITORIES: biostudies-literature