Opioid Prescription, Morbidity, and Mortality in US Transplant Recipients.

ABSTRACT:

Background

Centers for Disease Control and Prevention guidelines recommend caution in prescribing opioids for chronic pain. The characteristics of opioid prescription (OpRx) among kidney transplant (KTx) recipients have not been described in a national population.

Methods

We assessed OpRx prevalence among prevalent KTx recipients, and associated duration (long-term, defined as ≥90 days in a year) and dosing (in morphine milligram equivalents per day of <50, 50-89, and ≥90) with outcomes, death and graft loss, among incident KTx recipients using 2006-2010 US Renal Data System files, including Medicare Part D for medication ascertainment. Cox models controlled for recipient factors.

Results

Of 36,486 KTx recipients in the 2010 prevalent cohort, approximately 14.6% had l

SUBMITTER: Abbott KC 

PROVIDER: S-EPMC5962376 | biostudies-literature | 2018 Jun

REPOSITORIES: biostudies-literature