Profiling neurotransmitters in a crustacean neural circuit for locomotion.

ABSTRACT: Locomotor systems are widely used to study rhythmically active neural networks. These networks have to be coordinated in order to produce meaningful behavior. The crayfish swimmeret system is well suited to investigate such coordination of distributed neural oscillators because the neurons and their connectivity for generating and especially for coordinating the motor output are identified. The system maintains a fixed phase lag between the segmental oscillators, independent of cycle period. To further the understanding of the system's plasticity for keeping the phase lag fixed, we profiled the neurotransmitters used by the Coordinating Neurons, which are necessary and sufficient for coordination of the segmental oscillators. We used a combination of electrophysiological, immunohistochemic

SUBMITTER: Schneider AC 

PROVIDER: S-EPMC5963771 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature