Diabetic Retinopathy and Dementia in Type 1 Diabetes.

ABSTRACT:

Objective

Retinopathy impacts over one-third of those with diabetes mellitus and is associated with impaired cognitive performance and cerebrovascular lesions in middle-aged adults with type 1 diabetes. However, the association between diabetic retinopathy (DR) and risk of dementia in type 1 diabetes is unknown. We investigated the association between DR and incident dementia in a large, elderly population with type 1 diabetes.

Methods

A cohort of 3742 patients with type 1 diabetes aged 50 years and above was followed from January 1, 1996 to September 30, 2015 for incident dementia. DR diagnoses were identified from electronic medical records. Age as timescale Cox proportional hazard models evaluated associations between time-updated DR and dementia risk. Models were adjuste

SUBMITTER: Rodill LG 

PROVIDER: S-EPMC5963957 | biostudies-literature | 2018 Apr-Jun

REPOSITORIES: biostudies-literature