Feedforward Inhibition Conveys Time-Varying Stimulus Information in a Collision Detection Circuit.

ABSTRACT: Feedforward inhibition is ubiquitous as a motif in the organization of neuronal circuits. During sensory information processing, it is traditionally thought to sharpen the responses and temporal tuning of feedforward excitation onto principal neurons. As it often exhibits complex time-varying activation properties, feedforward inhibition could also convey information used by single neurons to implement dendritic computations on sensory stimulus variables. We investigated this possibility in a collision-detecting neuron of the locust optic lobe that receives both feedforward excitation and inhibition. We identified a small population of neurons mediating feedforward inhibition, with wide visual receptive fields and whose responses depend both on the size and speed of moving stimuli. By stud

SUBMITTER: Wang H 

PROVIDER: S-EPMC5964032 | biostudies-literature | 2018 May

REPOSITORIES: biostudies-literature