Pediatric Systemic Lupus Erythematosus: Learning From Longer Follow Up to Adulthood.

ABSTRACT: Background: Pediatric systemic lupus erythematosus (pSLE) is a rare condition, representing approximately 10% of SLE cases. The aim of this study was to identify variables to improve the diagnostic awareness and management of pSLE patients. Methods: This retrospective study included 25 patients diagnosed with pSLE and followed at the University of Pisa. We collected data about clinical profile at disease onset and during a long-term follow-up, including disease activity, organ damage development, and treatments received. Results: The mean patient age at disease onset was 14.6 ± 1.6 years, and the mean follow-up period was 14.17 ± 8.04 years. The most common initial manifestations were arthritis, malar rash, and cytopenias. The median time to diagnosis since the first s

SUBMITTER: Costagliola G 

PROVIDER: S-EPMC5964827 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature