Effect of Vitamin D Supplementation on Blood Pressure: A Systematic Review and Meta-analysis Incorporating Individual Patient Data.

ABSTRACT:

Importance

Low levels of vitamin D are associated with elevated blood pressure (BP) and future cardiovascular events. Whether vitamin D supplementation reduces BP and which patient characteristics predict a response remain unclear.

Objective

To systematically review whether supplementation with vitamin D or its analogues reduce BP.

Data sources

We searched MEDLINE, CINAHL, EMBASE, Cochrane Central Register of Controlled Trials, and http://www.ClinicalTrials.com augmented by a hand search of references from the included articles and previous reviews. Google was searched for gray literature (ie, material not published in recognized scientific journals). No language restrictions were applied. The search period spanned January 1, 1966, through March 31, 2014.

Study sel

SUBMITTER: Beveridge LA 

PROVIDER: S-EPMC5966296 | biostudies-literature | 2015 May

REPOSITORIES: biostudies-literature