A systematic review of the concept and clinical applications of Bone Marrow Aspirate Concentrate in Orthopaedics.

ABSTRACT: INTRODUCTION:Mesenchymal stem cells (MSC's) are believed to have multipotent plasticity with the capability to differentiate along multiple cell lineages such as cartilage, bone, tendon, muscle, and nerve. Such multipotency has the potential to play an important role in the repair and reconstruction of multiple tissues across a number of orthopaedic specialties. Bone marrow and fat are the most abundant and accessible source of MSC's with bone marrow aspirate the most commonly being reported to stimulate healing. METHODS:This review examines the current reported 20 Q2 clinical applications of bone marrow aspirate concentrate and its effectiveness. RESULTS:The published studies reported techniques of collection and preparation of BMAC in addition to its applications in a number of orthopaed

SUBMITTER: Imam MA 

PROVIDER: S-EPMC5966837 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature