Histamine activates inflammatory response and depresses casein synthesis in mammary gland of dairy cows during SARA.

ABSTRACT:

Background

Mounting evidences observed that subacute ruminal acidosis (SARA) induced by high concentration (HC) diet increases the translocation of histamine from digestive tract into circulation causing a diverse of diseases in dairy cows. However, it is largely unknown how it does affect the function of mammary gland and milk quality. Hence, this study aims to observe the effects of histamine derived from the digestive tract on the inflammatory response and casein synthesis in the mammary glands during SARA. Twelve cows fitted rumen fistula were randomly divided into either control group administrated low concentration (LC) diet (60% forage, n = 6) or treatment group administrated HC diet (40% forage, n = 6) for 18 weeks.

Results

Our data showed that HC diet resulted in si

SUBMITTER: Chang G 

PROVIDER: S-EPMC5966854 | biostudies-literature | 2018 May

REPOSITORIES: biostudies-literature