Assessment of Outer Retinal Remodeling in the Hibernating 13-Lined Ground Squirrel.

ABSTRACT:

Purpose

We examined outer retinal remodeling of the euthermic and torpid cone-dominant 13-lined ground squirrel (13-LGS) retina using optical coherence tomography (OCT) imaging and histology.

Methods

Retinas and corneas of living 13-LGSs were imaged during euthermic and torpid physiological states using OCT. Retinal layer thickness was measured at the visual streak from registered and averaged vertical B-scans. Following OCT, some retinas were collected immediately for postmortem histologic comparison using light microscopy, immunofluorescence, or transmission electron microscopy.

Results

Compared to OCT images from euthermic retinae, OCT images of torpid retinae revealed significantly thicker inner and outer nuclear layers, as well as increases in the distances betwe

SUBMITTER: Sajdak BS 

PROVIDER: S-EPMC5967598 | biostudies-literature | 2018 May

REPOSITORIES: biostudies-literature