Identification of alterations associated with age in the clustering structure of functional brain networks.

ABSTRACT: Initial studies using resting-state functional magnetic resonance imaging on the trajectories of the brain network from childhood to adulthood found evidence of functional integration and segregation over time. The comprehension of how healthy individuals' functional integration and segregation occur is crucial to enhance our understanding of possible deviations that may lead to brain disorders. Recent approaches have focused on the framework wherein the functional brain network is organized into spatially distributed modules that have been associated with specific cognitive functions. Here, we tested the hypothesis that the clustering structure of brain networks evolves during development. To address this hypothesis, we defined a measure of how well a brain region is clustered (network fi

SUBMITTER: Guzman GEC 

PROVIDER: S-EPMC5967704 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature