Relationship between degree of obstruction and airflow limitation in subglottic stenosis.

ABSTRACT:

Objectives

Subglottic stenosis (SGS) is one of the most common airway disorders in pediatric patients. Currently, treatment decisions rely primarily on the Cotton-Myer scale, which classifies SGS severity based on percentage reduction in airspace cross-sectional area (CSA). However, the precise relationship between upper airway resistance and subglottic CSA is unknown. We hypothesize that airway resistance can be described by the Bernoulli Obstruction Theory, which predicts that airway resistance is inversely proportional to airspace CSA ( R∝A-1) in cases of severe constriction.

Methods

Computed tomography (CT) scans of six healthy subjects and five SGS patients were used to create three-dimensional models of the respiratory tract from nostrils to carina. Cylindrical segment

SUBMITTER: Lin EL 

PROVIDER: S-EPMC5967982 | biostudies-literature | 2018 Jul

REPOSITORIES: biostudies-literature