A systematic review and meta-analysis of venous thrombosis risk among users of combined oral contraception.

ABSTRACT:

Background

Combined oral contraceptives (COCs) containing various progestogens could be associated with differential risks for venous thromboembolism (VTE).

Objective

To evaluate the comparative risks of VTE associated with the use of low-dose (less than 50 μg ethinyl estradiol) COCs containing different progestogens.

Search strategy

PubMed and the Cochrane Library were searched from database inception through September 15, 2016, by combining search terms for oral contraception and venous thrombosis.

Selection criteria

Studies reporting VTE risk estimates among healthy users of progestogen-containing low-dose COCs were included.

Data collection and analysis

A random-effects model was used to generate pooled adjusted risk ratios and 95% confidence interva

SUBMITTER: Dragoman MV 

PROVIDER: S-EPMC5969307 | biostudies-literature | 2018 Jun

REPOSITORIES: biostudies-literature