Residential proximity to major roadways and traffic in relation to outcomes of in vitro fertilization.

ABSTRACT:

Background

Emerging data from animal and human studies suggest that traffic-related air pollution adversely affects early pregnancy outcomes; however evidence is limited.

Objective

We examined whether residential proximity to major roadways and traffic, as proxies for traffic-related air pollution, are associated with in vitro fertilization (IVF) outcomes.

Methods

This analysis included 423 women enrolled in the Environment and Reproductive Health (EARTH) Study, a prospective cohort study, who underwent 726 IVF cycles (2004-2017). Using geocoded residential addresses collected at study entry, we calculated the distance to nearest major roadway and the traffic density within a 100 m radius. IVF outcomes were abstracted from electronic medical records. We used multivari

SUBMITTER: Gaskins AJ 

PROVIDER: S-EPMC5970056 | biostudies-literature | 2018 Jun

REPOSITORIES: biostudies-literature