Estimating Time to ESRD in Children With CKD.

ABSTRACT:

Rationale & objective

The KDIGO (Kidney Disease: Improving Global Outcomes) guideline for chronic kidney disease (CKD) presented an international classification system that ranks patients' risk for CKD progression. Few data for children informed guideline development.

Study design

Observational cohort study.

Settings & participants

Children aged 1 to 18 years enrolled in the North American Chronic Kidney Disease in Children (CKiD) cohort study and the European Effect of Strict Blood Pressure Control and ACE Inhibition on the Progression of CRF in Pediatric Patients (ESCAPE) trial.

Predictor

Level of estimated glomerular filtration rate (eGFR) and proteinuria (urine protein-creatinine ratio [UPCR]) at study entry.

Outcome

A composite event of renal replac

SUBMITTER: Furth SL 

PROVIDER: S-EPMC5970998 | biostudies-literature | 2018 Jun

REPOSITORIES: biostudies-literature