Direct Mapping of the QLQ-C30 to EQ-5D Preferences: A Comparison of Regression Methods.

ABSTRACT:

Background

Several mapping or cross-walking algorithms for deriving utilities from the European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire for Cancer (EORTC QLQ-C30) scores have been published in recent years. However, the large majority used ordinary least squares (OLS) regression, which proved to be not very accurate because of the specifics of the quality-of-life measures.

Objective

Our objective was to compare regression methods that have been used to map EuroQol 5 Dimensions 3 Levels (EQ-5D-3L) utility values from the general EORTC QLQ-C30 using OLS as a benchmark while fixing the number of explanatory variables and to explore an alternative three-part model.

Methods

We conducted a regression analysis of predicted EQ-5D-3L uti

SUBMITTER: Crott R 

PROVIDER: S-EPMC5972120 | biostudies-literature | 2018 Jun

REPOSITORIES: biostudies-literature