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<i>Gallid herpesvirus</i> 3 SB-1 strain as a recombinant viral vector for poultry vaccination.


ABSTRACT: Live herpesvirus-vectored vaccines are widely used in veterinary medicine to protect against many infectious diseases. In poultry, three strains of herpesvirus vaccines are used against Marek's disease (MD). However, of these, only the herpesvirus of turkeys (HVT) has been successfully developed and used as a recombinant vaccine vector to induce protection against other avian viral diseases such as infectious bursal disease (IBD), Newcastle disease (ND) or avian influenza (AI). Although effective when administered individually, recombinant HVT vectors have limitations when combined in multivalent vaccines. Thus there is a need for developing additional viral vectors that could be combined with HVT in inducing protection against multiple avian diseases in multivalent vaccines. Gallid her

SUBMITTER: Sadigh Y 

PROVIDER: S-EPMC5972151 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature