The relation of age at menarche with age at natural menopause: a population study of 336 788 women in Norway.

ABSTRACT:

Study question

Is age at menarche associated with age at menopause or with duration of the reproductive period (interval between menarche and menopause)?

Summary answer

The association of age at menarche with age at menopause was weak and non-linear, and the duration of the reproductive period decreased by increasing age at menarche.

What is known already

It remains uncertain whether age at menarche is associated with age at menopause. Some studies report that women with early menarche also have early menopause. Other studies report that women with early menarche have late menopause, or they report no association. The duration of the reproductive period may be an indicator of the cumulative endogenous exposure to estrogens and progestogens during life course and is as

SUBMITTER: Bjelland EK 

PROVIDER: S-EPMC5972645 | biostudies-literature | 2018 Jun

REPOSITORIES: biostudies-literature