Characterization of the transient middle cerebral artery occlusion model of ischemic stroke in a HuR transgenic mouse line.

ABSTRACT: This set of experiments characterizes a model of transient cerebral ischemic stroke in a transgenic (Tg) mouse line in which the glial fibrillary acidic protein (GFAP) promoter is utilized to drive expression of a human RNA-binding protein, HuR. Additionally, the effect of cerebral ischemia on the expression of endogenous Hu proteins is presented.

SUBMITTER: Ardelt A 

PROVIDER: S-EPMC5972843 | biostudies-literature | 2018 Feb

REPOSITORIES: biostudies-literature