Ontology highlight
ABSTRACT:
SUBMITTER: Hernandez MR
PROVIDER: S-EPMC5973623 | biostudies-literature | 2018 May
REPOSITORIES: biostudies-literature
Hernandez Margarita R MR Davis Michael B MB Jiang Jianhao J Brouhard Elizabeth A EA Severson Aaron F AF Csankovszki Györgyi G
PLoS genetics 20180516 5
Condensin complexes are key determinants of higher-order chromatin structure and are required for mitotic and meiotic chromosome compaction and segregation. We identified a new role for condensin in the maintenance of sister chromatid cohesion during C. elegans meiosis. Using conventional and stimulated emission depletion (STED) microscopy we show that levels of chromosomally-bound cohesin were significantly reduced in dpy-28 mutants, which lack a subunit of condensin I. SYP-1, a component of th ...[more]