The PL6-Family Plasmids of Haloquadratum Are Virus-Related.

ABSTRACT: Plasmids PL6A and PL6B are both carried by the C23^T strain of the square archaeon Haloquadratum walsbyi, and are closely related (76% nucleotide identity), circular, about 6 kb in size, and display the same gene synteny. They are unrelated to other known plasmids and all of the predicted proteins are cryptic in function. Here we describe two additional PL6-related plasmids, pBAJ9-6 and pLT53-7, each carried by distinct isolates of Haloquadratum walsbyi that were recovered from hypersaline waters in Australia. A third PL6-like plasmid, pLTMV-6, was assembled from metavirome data from Lake Tyrell, a salt-lake in Victoria, Australia. Comparison of all five plasmids revealed a distinct plasmid family with strong conservation of gene content and synteny, an average size

SUBMITTER: Dyall-Smith M 

PROVIDER: S-EPMC5974055 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature