Solute Carrier Family 30 Member 8 Gene 807C/T Polymorphism and Type 2 Diabetes Mellitus in the Chinese Population: A Meta-Analysis Including 6,942 Subjects.

ABSTRACT:

Background

Although solute carrier family 30 (zinc transporter) member 8 (SLC30A8) gene 807C/T polymorphism is associated with an increased risk of type 2 diabetes mellitus (T2DM) risk, there remains some inconsistency between individual studies.

Objective

The aim of the study is to explore the relationship between SLC30A8 gene 807C/T polymorphism and T2DM in the Chinese population.

Methods

The current meta-analysis compiles and analyzes the data of 6,942 participants from 10 independent studies. Either a fixed or random-effects model was adopted to evaluate the pooled odds ratio (ORs) and the corresponding 95% confidence interval (95% CI).

Results

A significant association between SLC30A8 gene 807C/T polymorphism and T2DM was found in the

SUBMITTER: Li YY 

PROVIDER: S-EPMC5974095 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature