EqualTDRL: illustrating equivalent tandem duplication random loss rearrangements.

ABSTRACT:

Background

To study the differences between two unichromosomal circular genomes, e.g., mitochondrial genomes, under the tandem duplication random loss (TDRL) rearrangement it is important to consider the whole set of potential TDRL rearrangement events that could have taken place. The reason is that for two given circular gene orders there can exist different TDRL rearrangements that transform one of the gene orders into the other. Hence, a TDRL event cannot always be reconstructed only from the knowledge of the circular gene order before a TDRL event and the circular gene order after it.

Results

We present the program EqualTDRL that computes and illustrates the complete set of TDRLs for pairs of circular gene orders that differ by only one TDRL. EqualTDRL considers the circ

SUBMITTER: Hartmann T 

PROVIDER: S-EPMC5975268 | biostudies-literature | 2018 May

REPOSITORIES: biostudies-literature