Hindering the formation and promoting the dispersion of medical biofilms: non-lethal effects of seagrass extracts.

ABSTRACT:

Background

Biofilms have great significance in healthcare-associated infections owing to their inherent tolerance and resistance to antimicrobial therapies. New approaches to prevent and treat unwanted biofilms are urgently required. To this end, three seagrass species (Enhalus acoroides, Halophila ovalis and Halodule pinifolia) collected in Vietnam and in India were investigated for their effects in mediating non-lethal interactions on sessile bacterial (Escherichia coli) and fungal (Candida albicans) cultures. The present study was focused on anti-biofilm activities of seagrass extracts, without killing cells.

Methods

Methanolic extracts were characterized, and major compounds were identified by MS/MS analysis. The antibiofilm properties of the seagrass extracts were teste

SUBMITTER: De Vincenti L 

PROVIDER: S-EPMC5975390 | biostudies-literature | 2018 May

REPOSITORIES: biostudies-literature