The spread of carbapenemase-producing bacteria in Africa: a systematic review.

ABSTRACT:

Background

Carbapenems are the last line of defence against ever more prevalent MDR Gram-negative bacteria, but their efficacy is threatened worldwide by bacteria that produce carbapenemase enzymes. The epidemiology of bacteria producing carbapenemases has been described in considerable detail in Europe, North America and Asia; however, little is known about their spread and clinical relevance in Africa.

Methods

We systematically searched in PubMed, EBSCOhost, Web of Science, Scopus, Elsevier Masson Consulte and African Journals Online, international conference proceedings, published theses and dissertations for studies reporting on carbapenemase-producing bacteria in Africa. We included articles published in English or French up to 28 February 2014. We calculated the preval

SUBMITTER: Manenzhe RI 

PROVIDER: S-EPMC5975721 | biostudies-literature | 2015 Jan

REPOSITORIES: biostudies-literature